Liver-D×1
Proenzi+×1
Colon-D×4The 21-Day Detox is a three-phase kit: a 5-day colon cleanse with COLON-D and PROENZI+, a 2-day liver flush with Liver-D, and a 14-day guided eating plan with no sugar or refined carbohydrates. Four COLON-D bags, one Liver-D (Liver Support + Liver Mix) and 60 PROENZI+ capsules: everything you need for the full 21 days, with a day-by-day guide.
Most detox programs are a box of tea bags and a promise. Here is how the 21-Day Detox compares to typical detox programs.
21-Day Detox
Phase 1 starts with COLON-D, a 100% botanical infusion of persimmon, mallow, marshmallow, holy thistle and blessed thistle leaves. The mucilage-rich leaves soothe the intestinal lining and give a mild laxative effect, while the thistles support liver function. Every cup goes with a PROENZI+ capsule: three Lactobacillus strains (acidophilus, casei and plantarum at 48 billion CFU/g each), Aspergillus protease and five digestive enzymes (bromelain, papain, lipase, lactase and alpha galactosidase at 24,000 U/g each) that break down what you eat and help replenish your gut flora.
Phase 2 is the Liver-D flush, two bottles made to work together. Liver Support is a powder that delivers, per serving (4 per bottle), 2,940 mg of vitamin C and a 9.31 g blend of magnesium sulfate, yucca root, artichoke, dandelion, milk thistle, ginger and turmeric root extract with 95% curcuminoids; the whole bottle is mixed in apple juice and taken in four doses. Liver Mix is 118 ml of extra virgin olive oil with vitamin E (100% DV), shaken with fresh lemon juice and taken all at once at 10:00 pm. Phase 3 puts the cleanse to work: 14 days of a guided eating plan with no sugar or refined carbohydrates, still with COLON-D and PROENZI+ before each meal.
Your liver filters your blood, produces bile, stores nutrients and processes what you eat, drink and breathe, around the clock. Your colon finishes the job, moving waste along and absorbing the last water and minerals. When either one slows down under processed food, alcohol, medication or stress, you feel it as heaviness, bloating, gas and low energy. The 21-Day Detox works in that order: it clears the colon first, so the liver flush on days 6 and 7 has a clear path, and then feeds both with 14 days of real food.
It is a periodic reset, not a daily supplement. The guide sets the exact times of every dose, and the eating plan gives you daily menus with three meals and two snacks and an allowed-foods list so you know what to put on the plate for the two weeks that make the results last.

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Everything you need to know about the 21-Day Detox
The 21-Day Detox (21D Challenge / Reto 21D) is a three-phase program that combines three iEvolution products with a guided eating plan:
It is designed to start on a Monday, so the liver flush falls on Saturday and Sunday.
One kit covers the full 21 days:
COLON-D (per bag): persimmon leaves, mallow leaves, holy thistle, marshmallow leaves and blessed thistle. Other ingredients: silicon dioxide. 2 calories, 0 g fat, 0 g sugar.
Liver Support (per 12.25 g serving, 4 per bottle): vitamin C (ascorbic acid) 2,940 mg and 9.31 g of the iEvo liver detox blend: magnesium sulfate USP, yucca root, artichoke 4:1 extract, dandelion 4:1 extract, milk thistle extract, ginger root and turmeric root extract with 95% curcuminoids.
Liver Mix (1 bottle, 118 ml): extra virgin olive oil 118 ml and vitamin E 25.35 IU (100% DV).
PROENZI+ (per 480 mg capsule): Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus plantarum and Aspergillus fungal protease at 48 billion CFU/g each; bromelain, papain, fungal lipase, fungal lactase and alpha galactosidase at 24,000 U/g each. Gluten-free, Non-GMO, no additives.
Liver-D is two bottles that work as a pair. Liver Support is a powder you mix in 24 oz (710 ml) of organic apple juice at 3:00 pm on day 6 and drink in four 6 oz (178 ml) doses: 6:00 pm, 8:00 pm, on waking on day 7 and 10:00 am. Its magnesium sulfate and vitamin C prepare the digestive tract, and the artichoke, dandelion, milk thistle, ginger and turmeric support liver function and bile flow.
Liver Mix is 118 ml of extra virgin olive oil with vitamin E. At 10:00 pm on day 6 you shake it with 4 oz (120 ml) of fresh lemon juice, drink it all at once and lie on your right side to sleep. During these two days you stop the COLON-D tea, eat light (chicken broth with vegetables) and skip dinner on day 6 and breakfast on day 7. Bowel movements may increase after the evening doses: plan to stay home.
All three products are made with natural ingredients, and the program is a periodic cleanse, not for continuous daily use. It is for adults only: iEvolution does not recommend it for anyone under 18 or under 100 lb (50 kg) of body weight.
Do not do the cleanse if you are pregnant or nursing, or if you have active gallstones, a bile duct obstruction or a severe liver disease such as active hepatitis or cirrhosis: the artichoke, dandelion and milk thistle in Liver Support and the olive oil in Liver Mix stimulate bile flow, and Liver Support contains magnesium sulfate, which already has a marked laxative effect. Do not combine it with other laxatives, cleansers or digestive supplements, and do not exceed the stated doses.
Talk to your doctor first if you take any medication, especially anticoagulants such as warfarin (turmeric and vitamin E can add to their effect) or drugs processed by the liver; if you have diabetes or high blood glucose (mix Liver Support in purified water instead of apple juice and follow your doctor’s dietary guidance); or if you have high blood pressure, a heart or thyroid condition, or any digestive condition. Bromelain comes from pineapple and papain from papaya: if you are allergic to either fruit, ask your physician before taking PROENZI+. COLON-D has no caffeine. Increased bowel movements are expected during the flush; stay well hydrated the whole time. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Days 1–5: eat normally, but go easy on processed food and heavy carbohydrates, and take your tea and PROENZI+ 20 minutes before each meal.
Days 6–7: follow the specific meal guidance: light breakfast on day 6 (scrambled eggs, a little fruit), chicken broth with vegetables and some shredded chicken for lunch, no dinner. On day 7 skip breakfast and keep lunch and dinner light. Avoid bread, rice, tortillas and sugar.
Days 8–21: follow the eating guide. It removes sugar and refined carbohydrates and replaces them with protein, vegetables and healthy fats, with daily menus of three meals and two snacks and an allowed-foods list. You eat when you are hungry; you do not have to finish every menu.
Results vary from person to person. The products are formulated to support regular bowel movements, a lighter digestion, relief from occasional gas and bloating, and normal energy levels. The two weeks of Phase 3 are what make the change last: they turn the cleanse into habits.
The 21-Day Detox is a periodic reset, not a daily supplement. iEvolution recommends repeating the full program every 3 to 4 months. Between challenges you can keep taking PROENZI+ daily for digestive support and use COLON-D occasionally.
The 7-Day Detox covers only phases 1 and 2: the colon cleanse and the liver flush, the first seven days of this program. It includes Liver-D, one COLON-D bag and 15 PROENZI+ capsules.
The 21-Day Detox adds the 14-day eating plan and the supplies to go with it: four COLON-D bags and 60 PROENZI+ capsules, so you keep the tea and the capsules before every meal through day 21. If you want a quick weekend reset, choose the 7-Day. If you want to change how you eat afterward, choose the 21-Day.
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